Development of High Efficient New Production Process for Proteins
- 2014/02/25 News
무료 바카라emical has developed the high efficient production process for proteins by applying our strong points of surfactant technologiesEscherichia coli ( Ewhich has not been impossible hithertoE.coliOur process enables to improve the productivity of proteins and extends the possibilities of industrial use of the valuable proteins which have not been obtained enough in industrial scale so far
Conventional problems
Generally it is well known as the production method for proteins by expression of the target inE.coliand taking it out after destruction the cell membraneE.coliBut its production capacity is limited because the target protein is expressed only inside the cell and never secreted outsideE.colito take out the protein
The other method is also available that is producing extracellular proteins by usingBacillus subtilisorAspergillus oryzaeHowever its versatility is extremely low because the proteins which can be applied to are limitedE.colithe most versatile bacteria for production of recombinant proteins
Abstract of the new technology
Our development realized extracellular production of recombinant proteins usingE.coliby applying our strong points of surfactant technologiesE.coli’sThis enables to establish the new extracellular producing process of the proteins usingE.coliour development extends the possibility of the industrial use of the valuable proteins which have not been obtained enough in industrial scale so far
Fields of application
We expect that our technology contribute to the many fields such as pharmaceuticals
Future plans
We have constructed about a 100L test facility on laboratory scale and started the several collaborative studies for the industrial production
We are trying to assist the productions of various proteins through flexible corresponding to various needs by collaborative studies